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Evaluate corneal rigidity changes following corneal crosslinking (CCL) by paired differential tonometry IOP measurements with a Goldmann tonometer (GAT) using both a standard GAT prism and corneal compensating GAT prism.
IOP was measured on 18 unique eyes undergoing CCL for keratoconus with a GAT using a standard flat prism and a curved corneal error correcting prism before treatment and 2 weeks, 2 months and 6 months after treatment. Concurrent measurements of Central corneal thickness CCT and corneal hysteresis CH were completed.
Paired IOP measurements with standard and corneal correcting GAT prisms indicated a significant sustained relative increase in the differential IOP between the two prisms after CCL (p=0.005,0.015). CH initially decreased at two weeks post-CCL then returned to sustained pre-op levels (p=0.033,0.20). CCT progressively decreased following CCL (p=0.002).
Differential tonometry between standard and corneal biomechanical compensating GAT prisms demonstrated it as a simple and sensitive measurement of changes in corneal rigidity and corneal stress redistribution.