Analysis of Correlation between Chromatic and Achromatic Contrast Sensitivity, and Higher-Order Aberrations after SMILE, LASIK, and PRK | ASCRS
Presentation
Analysis of Correlation between Chromatic and Achromatic Contrast Sensitivity, and Higher-Order Aberrations after SMILE, LASIK, and PRK
May 2020
Meeting: 2020 Virtual Annual Meeting
Session: SPS-114 Keratorefractive Surgical Planning
Author: Seongjun Lee, MD
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Purpose
To investigate the relation between induced changes in higher-order aberrations (HOAs) of the cornea and changes in contrast sensitivity (CS) by SMILE, LASIK, and PRK

Methods
In 237 eyes of 136 patients having a UCVA of more than 20/25, residual spherical equivalent within ± 1.00 D after SMILE, LASIK, or PRK, HOAs and CS function were investigated before and 6 months after surgery. The amount of myopic correction was 4.87 ± 1.71 D (range, 0.63 - 9.63). Spherical aberration (SA), coma and residual HOAs were measured for a 6-mm pupil using a corneal wavefront analyzer (OPTIKON 2000, Rome, Italy). The cone CS (CCT HD, Konan medical, CA) was used to measure the mean L, M and S-CCT scores as the chromatic contrast, and the area under the log contrast sensitivity function (AULCSF) as the data of the achromatic contrast under the photopic and low mesopic condition.

Results
At 6 months postoperatively, the SMILE and LASIK showed no correlation, but PRK showed a negative correlation between the changes of SA and the changes of chromatic contrast, this can be seen in the following test scores of L, M and S-CCT (r=-0.479, p=0.024, r=-0.515, p=0.014, r=-0.456, p=0.033, respectively). All of the three groups showed no correlation between the changes of SA and the changes of photopic achromatic CS but, SMILE (r=0.227, p=0.035) and PRK (r=-0.512, p=0.015) showed correlation between the changes of SA and the changes of low-mesopic achromatic CS. PRK showed correlation between the changes of residual HOAs and the changes of low-mesopic achromatic CS (r=-0.585, p=0.007).

Conclusion
SMILE results in significantly less induced higher-order aberrations than PRK. In SMILE and LASIK, there was no tendency that the contrast sensitivity was decreased when the higher-order aberrations were increased, but in PRK, chromatic and low-mesopic achromatic contrast tended to be decreased when the higher-order aberrations were increased.
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This presentation is from the session "SPS-114 Keratorefractive Surgical Planning" from the 2020 ASCRS Virtual Annual Meeting held on May 16-17, 2020.

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