Femtosecond Laser Astigmatic Keratotomy Analyzed By Machine Learning | ASCRS
Femtosecond Laser Astigmatic Keratotomy Analyzed By Machine Learning
May 2020
Meeting: 2020 Virtual Annual Meeting
Session: SPS-102 Toric IOLs - Astigmatism
Author: Gerald P. Clarke, MD
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To analyze femtosecond laser arcuate keratotomy (FLAK) using modern machine learning techniques, thereby finding important corneal variables affecting results, and algorithms to better predict results.

125 retrospective patient records were analyzed with preoperative topography, FLAK with iris registration and cataract surgery with recording of 2.4 mm incision was performed, and postop topography recorded minimum 6 weeks postop. Results were analyzed using Alpins analysis. SIA was measured, and a new definition of Moment was developed. Moment measures the resultant misalignment of SIA from TIA. SIA magnitude was the first outcome measure, and all variables were entered into a machine learning ensemble. A mixed model was developed to predict SIA magnitude, and second model predicted Moment. A 2 stage genetic algorithm predicts best parameters to predict desired SIA and smallest Moment.

A machine learning ensemble 92% weighted with a linear model, predicted SIA magnitude with Rsquared= 0.89, and the Moment with Rsquared = 0.88; The most important variables are Ks at 3mm, Total Corneal Astigmatism, including posterior astigmatism, and Q shape Factor.

Machine Learning can use all corneal variables to arrive at better predictive models to predict the FLAK SIA magnitude, and the risk of misalignment of the SIA angles.
View More Presentations from this Session

This presentation is from the session "SPS-102 Toric IOLs - Astigmatism" from the 2020 ASCRS Virtual Annual Meeting held on May 16-17, 2020.

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