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To evaluate endothelial cell density, loss and stability over a three-year period in patients who have undergone ab-interno canal based surgery using the iTrack surgical system (Ellex, Adelaide, Australia).
Prospective, multi-center registry study with patients undergoing iTrack ab-interno canal based surgery, either as a standalone procedure or in combination with cataract surgery. Specular microscopy was performed preop and at 1, 6, 12, 24, and 36 months postop. Standard metrics for glaucoma surgery follow-up were also measured including; visual acuity, IOP, visual fields, optic nerve OCT and glaucoma medication use. Endothelial cell density and loss were analyzed at each time point. Results from patients undergoing iTrack combined with cataract surgery were compared with results from age matched controls who underwent cataract surgery only. Six month results are being reported.
Mean endothelial cell loss 1 month following iTrack surgery was 4%, 2% as a standalone procedure and 5% in combination with cataract surgery. Endothelial cell loss in the age matched control group undergoing cataract surgery alone was 5%. There was no additional endothelial cell loss between months 1 and 6 in any group.
iTrack canal based surgery causes minimal endothelial cell loss, comparable to cataract surgery alone. Future analyses will assess longer term endothelial cell stability.
This presentation is from the session "SPS-105 Minimally Invasive Glaucoma Surgery: Viscocanalostomy, Combined Procedures, Outcomes" from the 2020 ASCRS Virtual Annual Meeting held on May 16-17, 2020.