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To demonstrate the efficacy of cross linking of donor corneas in resisting post operative infections and corneal melts in Boston Type 1 Keratoprosthesis in eyes with ocular surface disorders.
Prospective observational case series.A conventional epithelium off corneal collagen cross linking was performed with riboflavin and UV light, in a de-epithelialized donor cornea mounted on an artificial anterior chamber, subsequently the cornea is used as a carrier for Boston Type 1 keratoprosthesis, and transplanted in eyes with OSD and multiple failed corneal grafts. The patients were followed up for corneal integrity to resist infection and corneal melts, which are common following Boston Keratoprosthesis and especially in cases of OSD.
16 cases of 15 subjects were studied, followed-up of 5 years. All grafted eyes were healthy in resisting long term post operative infections and corneal melts.
Cross linking of donor corneal button before Boston Type 1 Keratoprosthesis with Riboflavin and UV rays is effective in improving long term post operative strength and outcome of corneas, especially in cases of ocular surface disorders